Haderm 10ml – High-Capacity Cross-Linked Hyaluronic Acid Filler

                                                               www.dermalfillerbotox.com

Haderm 10ml – High-Capacity Cross-Linked Hyaluronic Acid Filler

Technical Datasheet & Product Summary for Clinical Use

---

🧪 Product Definition

Haderm 10ml is a sterile, apyrogenic, viscoelastic injectable gel based on cross-linked hyaluronic acid of non-animal origin, developed for deep dermal and subcutaneous tissue augmentation. Its large volume capacity (10ml per syringe) is specifically formulated for professional use in full-face volumization and structural correction.

The filler offers high cohesivity and moderate viscosity, ensuring stable projection, natural integration, and minimal migration post-injection.

---

📊 Technical Specifications

Parameter	Specification
Formulation	Cross-linked Sodium Hyaluronate
HA Concentration	24 mg/ml
Volume	10 ml (1 pre-filled syringe)
Cross-Linking Agent	BDDE (1,4-Butanediol Diglycidyl Ether)
pH Level	7.0 ± 0.5
Osmolality	~280–300 mOsm/kg
Viscosity	Medium-High
Elastic Modulus (G')	Approx. 180–220 Pa
Sterilization Method	Moist heat (autoclaving)
Shelf Life	24 months (unopened, at 2–25°C)

---

💉 Injection Protocol

Area	Depth	Suggested Tool
Cheeks	Deep dermis / supraperiosteal	25G cannula or 27G needle
Jawline	Subcutaneous / deep dermis	23G–25G cannula
Chin	Supraperiosteal	25G cannula or needle
Temples	Deep temporal fat pad	25G cannula
Nasolabial folds	Mid to deep dermis	27G needle

Perform aspiration techniques where applicable. Inject slowly and symmetrically.

---

⚙️ Mechanism of Action

Haderm 10ml acts by restoring volume through hydrophilic expansion and spatial occupation within the dermal or subdermal matrix. The cross-linked HA resists enzymatic degradation, providing extended longevity. BDDE-crosslinking increases mechanical strength and structural integrity, making it suitable for load-bearing facial areas.

---

⏱️ Duration of Effect

• Clinical results typically last 12 to 18 months depending on:

  • Treatment area

  • Injection technique

  • Patient metabolism and lifestyle

  • Depth and volume used

---

🔒 Safety & Biocompatibility

• Non-animal origin (bacterial fermentation-derived HA)

• CE-certified according to EU Medical Device Regulation (MDR)

• Free from endotoxins (<0.5 EU/mL)

• BDDE residue within EU safety limits (<2 ppm)

• Compatible with human tissues – low risk of hypersensitivity

---

📦 Packaging Information

• 1 x 10ml pre-filled sterile syringe

• 2 x sterile needles (optional, depending on distributor)

• Individually boxed with IFU (Instructions for Use)

---

🧑‍⚕️ Target User Group

• Medical professionals specialized in:

  • Aesthetic dermatology

  • Cosmetic surgery

  • Advanced facial anatomy & volumization

  • Non-surgical facial contouring

---

📈 Clinical Use Cases

• Global facial harmonization

• Structural framework augmentation

• Correction of age-related volume loss

• Jawline sculpting / chin definition

• Temple hollow correction

• Combination therapy with biostimulators or skin boosters (in separate layers)

---

⚠️ Contraindications

• Active skin infection in treatment area

• Known hypersensitivity to hyaluronic acid or BDDE

• Autoimmune diseases or uncontrolled systemic disorders

• Anticoagulant therapy (relative contraindication)

---

                                                     www.dermalfillerbotox.com

#Haderm10ml #ProfessionalFiller #HyaluronicAcidFiller #MedicalGradeFiller #CrossLinkedHA #FacialVolum